The SNPs found on that particular gene are speeding up the gene function in a certain way.įor example, a gene may be faster because it is more sensitive to being produced, may be more sensitive to the cofactor or it may be more sensitive to the substrate. A combination of a more sensitive histamine receptor and slower elimination of histamine may explain why you are so susceptible to various high histamine symptoms like seasonal allergies. If you have a ‘slow’ HNMT and ‘slow MAOA’ and ‘slow ALDH Family’ genes, then you may be more susceptible to higher histamine. This informs that you should work to have healthy histamine levels - not too high. If you have an ‘orange’ HRH1 receptor SNP, then you may be more sensitive to histamine. You optimize their speed depending on what health goal you are targeting.įor example, if you’re struggling with high histamine symptoms, you look at your histamine pathway. It simply informs you how your genes are susceptible to working faster, slower or more typical. The notable variation gives you more precise information. The speed dial is just a fast way to get a quick and dirty understanding of your pathway as a whole. Clicking that gene gives you the ability to read the specific ‘notable variation’. This is why we also include the epigenetic influences on each gene in orange and purple - not just the SNP speed dial.Īfter you get your quick glance of the speed dials and their associated colors, you must then click that particular gene. They do not take any lifestyle, environmental, nutritional or dietary influences. Important: Speed dials only take into account the effect of the SNP. Are the SNPs and their associated speed dials slowing or speeding up certain areas of the pathway? What are the potential consequences of that? Each pathway gives you an immediate idea of how each SNP is impacting its overall function. We display the colored speed dials on a pathway (a diagram of how a set of genes work together). Since genes work together, it’s important to see them together versus on their own. There is a color associated with each speed. Your gene’s function may be slower, faster, intermediate, or complicated. Your StrateGene report uses speed dials with various colors making it easier to see how a SNP influences each gene. What you need to know is ‘How does this SNP influence my specific gene?’ This information is not informative nor does it give you insight into what actions you should consider. Most genetic reports focus on whether or not a gene has SNPs that are homozygous, heterozygous or wild-type.
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